Gene information
Official symbol TNFRSF10B
Official full name TNF receptor superfamily member 10b
Gene type protein-coding gene
Chromosome8p21.3
Alias symbolDR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2
Gene familyCD molecules; Tumor necrosis factor receptor superfamily
Resources
Entrez Gene 8795
HGNC HGNC:11905
Ensembl ENSG00000120889
Vega OTTHUMG00000097826
UCSC uc003xcu.4
GO terms: 15 records
GO Description Category LogP Number of genes Detail
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0032147 activation of protein kinase activity GO Biological Processes -11.6086663 28 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0038061 NIK/NF-kappaB signaling GO Biological Processes -4.66781085 9 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0071496 cellular response to external stimulus GO Biological Processes -17.0078490 52 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097193 intrinsic apoptotic signaling pathway GO Biological Processes -4.54525889 10 More
KEGG pathways: 10 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04061 Viral protein interaction with cytokine and cytokine receptor KEGG Pathway -30.3399237 29 More
hsa04115 p53 signaling pathway KEGG Pathway -6.32340535 9 More
hsa04210 Apoptosis KEGG Pathway -6.60042966 12 More
hsa04217 Necroptosis KEGG Pathway -8.49909048 15 More
hsa04650 Natural killer cell mediated cytotoxicity KEGG Pathway -3.46704202 8 More
hsa05130 Pathogenic Escherichia coli infection KEGG Pathway -9.84822677 18 More
hsa05132 Salmonella infection KEGG Pathway -7.42305681 17 More
hsa05164 Influenza A KEGG Pathway -16.0885267 23 More
hsa05417 Lipid and atherosclerosis KEGG Pathway -33.3876857 40 More
Drug-Gene interaction
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Related drugs: 7 records
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
tumor necrosis factor receptor superfamily member 10B proteomics death[prognosis (bad)] acute myocardial infarction Skau E et al. Eur J Prev Cardiol. 2017
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